Department of Ophthalmology, Grigore T. E-mail: moc.
We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell arata viermi copilului of the conjunctiva of the left eye.
The method used for the detection of HPV was real time polymerase chain reaction.
The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward papillomavirus lesions treatment two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells. Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for the last 2 months papillomavirus lesions treatment dexamethasone eye drops for scleritis by another ophthalmologist. The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal.
Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes.
The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas papillomavirus lesions treatment chain reaction PCR solution and refrigerated at 4°C until processing.
Având Ana Maria their health status. In men, the subclinical HPV în vedere faptul că la bărbaţi infecția subclinică este Medeleanu1, infection is 10 times more frequent then the de peste 10 ori mai frecventă decât cea simptomatică, Cristiana symptomatic one, therefore the diagnosis often papillomavirus lesions treatment acesteia necesită, de papillomavirus lesions treatment mai multe ori, Voicu1, requires special procedures and techniques. Datele din literatură arată o incidenţă dintre cele mai răspândite infecții cu transmisie se- anuală a infecţiei genitale cu HPV definită papillomavirus lesions treatment pre- xuală la nivel global, o patologie întâlnită frecvent papillomavirus lesions treatment vegetaţiilor localizate la cancerul femural vulvei, papillomavirus lesions treatment la nivelul tractului genital feminin şi masculin, cu ului, zonei perianale, vaginului, cervixului, penisului, sau fără leziuni clinice 1. HPV se limitează la nivelul scrotului şi uretrei de de cazuri noi la La pacienții imunocompentenți, imunitatea celulară Aproximativ jumătate dintre adulţii activi din punct poate controla infecția papillomavirus lesions treatment cu HPV şi poate induce de vedere sexual prezintă infecţie subclinică cu una sau regresia leziunilor induse de acest virus 4însă în anu- mai multe tulpini de HPV, majoritatea tulpini benigne.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.