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It has been demonstrated that the human papillomavirus HPV type 16, a subtype of the human papillomavirus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive.
HPV-infected cells express some viral proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type protein RBP involved in the regulation of proliferation and cell death.
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În India constituie cea mai frecventă formă de cancer. Cu toate acestea, în ultima decadă, date clinice şi hpv and head and neck cancer au documentat asocierea dintre infecţia HPV papiloma virus uman a cavităţii orale şi OSCC2;3;4;5.
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